What is the most typical microorganism cultured from surgical site infections (SSIs)?

The most typical microorganism cultured from surgical site infections (SSIs) is Staphylococcus aureus. This pathogen is commonly involved in SSIs due to its prevalence on human skin and mucous membranes, making it easily introduced into surgical wounds. Its ability to form biofilms and produce various toxins contributes to its virulence, leading to both superficial infections and more severe, deep tissue infections after surgery.

Staphylococcus aureus is particularly notorious for causing complications because it can survive harsh environments and resist certain antibiotic treatments, complicating the management of infections. While other organisms like Escherichia coli and Staphylococcus epidermidis can also be implicated in SSIs, Staphylococcus aureus remains at the forefront as a key pathogen associated with these infections, especially in surgical settings. Clostridium perfringens, while a serious pathogen, is less commonly associated with general SSIs but is more noted for specific types of necrotizing infections.